Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

A high-resolution recombination map of the human genome

Detection of large-scale variation in the human genome

A rice quantitative trait locus for salt tolerance encodes a sodium transporter

Principal components analysis corrects for stratification in genome-wide association studies

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

Convergent adaptation of human lactase persistence in Africa and Europe

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

This study, cited over 1,400 times, identified variants in FLG accounting for a large proportion of atopic dermatitis cases in Europeans and a subset of asthma that co-occurs with atopic dermatitis. These findings indicated for the first time that genes with function in the skin, rather than immune-related genes, could contribute to asthma development.

http://www.nature.com/content/NatureGenetics_25th_Anniversary/index.html?WT.mc_id=FBK_NG_1704_Anniversary25_Portfolio